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French National Academies say Seralini Study Means…Nothing.

logo_france_academie_small-21The French national academies of sciences, technology, medicine, pharmacy, veterinary studies and agriculture have dismissed the controversial study of genetically modified corn conducted by their countryman Gilles-Eric Seralini as meaningless, and chastised him for spreading fear among the public. They also expressed disappointment in the peer-review process that allowed the study to be published in a mainstream scientific journal.

In a joint statement - something described by the French news service AFP as an “extremely rare event in French science” - the academies described the study as a “scientific non-event” that “does not enable any reliable conclusion to be drawn” from its findings. Seralini and his colleagues at the University of Caen claimed that a diet of the genetically modified corn known as NK603 caused laboratory rats to develop tumors.

“Given the numerous gaps in methods and interpretation, the data presented in this article cannot challenge previous studies which have concluded that NK603 corn is harmless from the health point of view, as are, more generally, genetically modified plants that have been authorized for consumption by animals and humans,” said the statement from the French academies, which are learned societies that advise the government, equivalent to the National Academies in the United States. READ MORE »

Dr. Oz promotes discredited rat study

dr-oz1Dr. Mehmet Oz gave credence Wednesday to a controversial study that the scientific community has thoroughly discredited, much to the dismay of scientists who hoped for a fact-based discussion of genetically modified food on his syndicated TV program.

“We find these claims and corresponding graphic representations to be highly misleading and irresponsible,” said a statement published by 17 scientists, researchers, and health professionals.

In a 20-minute segment devoted to genetically modified foods, Oz interviewed a physician named Robert Bernhoft, who praised a study by the French anti-biotech activist Gilles-Eric Seralini claiming that genetically modified corn caused lab rats to grow tumors.

Dr. Oz displayed photos of the rats with enormous tumors but failed to mention that the study has been rejected as unscientific by the European Food Safety Authority and other scientific agencies and didn’t mention the fact that the type of rats used in the study typically develop tumors as they age, regardless of their diet.

“The rats shown on the Oz show are a strain that has a very high incidence of cancer, and would have developed the same proportion of cancers no matter what (they were) fed - including organic food and herbal teas, or whatever,” said Professor Jonathan Gressel of Weizmann Institute of Science in Israel. “If Dr. Oz is a competent medical practitioner, he surely should have known that.” READ MORE »

German risk assessment agency shreds Séralini rat study

german-risk-assesmentA widely-criticized study by a French team claiming that genetically modified corn caused laboratory rats to develop tumors has been thoroughly rebutted by an agency of the German government, which said the “study” is full of holes and reaches conclusions that are not supported by the data, which the agency said was inadequate and badly presented.

“The study shows both shortcomings in study design and in the presentation of the collected data,” said Professor Dr. Reiner Wittkowski, vice president of the Federal Institute for Risk Assessment (BFR), an agency of the Federal Ministry of Food, Agriculture and Consumer Protection (BMELV). The agency advises the German federal government and state governments on questions of food, chemical and product safety. “This means that the conclusions drawn by the authors are not supported by the available data,” Wittkowski said. READ MORE »

Scientists in U.S. Reject Heavily Publicized Rat Study; Other Studies Show No Impact of Feeding Biotech Grain

A bizarre study by French researchers claiming ill effects on laboratory rats fed genetically modified corn and given water spiked with herbicide has been rejected by American scientists who questioned the motives and methods of the authors.

“This study appears to be without scientific merit,” said Dr. Martina Newell-McGloughlin, director of the International Biotechnology Program at the University of California/Davis. “The problem here appears to be with the experimental design,” she said. “Whether it was deliberately devised to attain the desired outcome remains to be seen.”

“This is not an innocent scientific publication,” Dr. Bruce M. Chassy, professor emeritus of food science at the University of Illinois, said. “It is a well-planned and cleverly orchestrated media event. The study was designed to produce exactly what was observed and it was deliberately allowed to continue until grotesque and fear-evoking tumors developed. The way the study was conducted, including the treatment of the animals, especially those who developed tumors as these rats are known to do, raises serious ethical concerns and profound questions of possible scientific misconduct.” READ MORE »

Problems seen in anti-biotech study

CBI has pointed out some of the shortcomings of a paper claiming previously unheard-of health impacts on rats on a diet of biotech corn and weedkiller- a study that some experts think is so questionable that it should not have been published.

“The study published today is a continuation of work that has been denounced by responsible scientific bodies and by scientists who know the subject very well,” the CBI statement said of a paper by Gilles-Eric Seralini, a French biologist, author, and long-time anti-biotech activist.

“Studies by independent scientists have found again and again that food from plants produced with biotechnology is as safe as the same plants produced by conventional means,” the CBI statement said. “More than 400 studies have confirmed the safety of food with biotech ingredients, and not one has documented any ill effect to human health of eating food produced in whole or in part with biotechnology.

Scientists in Europe have pointed out a host of flaws in the current study, including the fact that the rats chosen for the study are known for their tendency to develop tumors. A previous study by Seralini was denounced as invalid by the European Food Safety Authority (EFSA), and experts are very critical of the statistical methods employed in the new study.

“To be honest, I am surprised it was accepted for publication,” said Prof. David Spiegelhalter of the University of Cambridge in England.

Seralini claimed that this was the first long study based on feeding biotech grain to animals. In fact, several other studies as long or longer have concluded that there is no impact from biotech food or feed ingredients, according to a major study published earlier this year in the very same journal that published Seralini’s study (”Food and Chemical Toxicology). Experts were reported to the “skeptical” of the latest from Seralini.

The Reuters news agency reported:

Tom Sanders, head of the nutritional sciences research division at King’s College London noted that Seralini’s team had not provided any data on how much the rats were given to eat, or what their growth rates were.

“This strain of rat is very prone to mammary tumors particularly when food intake is not restricted,” he said in an emailed comment.

“The statistical methods are unconventional and probabilities are not adjusted for multiple comparisons. There is no clearly defined data analysis plan and it would appear the authors have gone on a statistical fishing trip.”

European Food Safety Authority (EFSA), commenting on a previous Seralini study, said:

“Following a detailed statistical review and analysis by an EFSA Task Force, EFSA’s GMO Panel has concluded that this re-analysis of the data does not raise any new safety concerns.” EFSA noted that “The statistical analysis made by the authors of the paper did not take into account certain important statistical considerations. The assumptions underlying the statistical methodology employed by the authors led to misleading results. EFSA considers that the paper does not present a sound scientific justification in order to question the safety of (the) maize.”

Prof. David Spiegelhalter, Winton Professor of the Public Understanding of Risk, University Of Cambridge, gave this statement to the media:

“In my opinion, the methods, stats and reporting of results are all well below the standard I would expect in a rigorous study - to be honest I am surprised it was accepted for publication.

“All the comparisons are made with the ‘untreated’ control group, which only comprised 10 rats of each sex, the majority of which also developed tumors. Superficially they appear to have performed better than most of the treated groups (although the highest dose GMO and Roundup male groups also fared well), but there is no proper statistical analysis, and the numbers are so low they do not amount to substantial evidence. I would be unwilling to accept these results unless they were replicated properly.” Read more.

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